Hypoglyceamic activity of Alstonia boonei stem bark extract in mice

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Formulation and Evaluation of Alstonia boonei Stem Bark Powder Tablets

The aim of this work was to formulate Alstonia boonei dried stem bark powder into tablets by wet granulation method using acacia, gelatine and sodium carboxymethyl cellulose as binders at concentrations of 1, 2, 4 and 8% w/w. The phytochemistry of the stem bark of Alstonia boonei was evaluated. The micromeritic properties of the granules prepared were studied. The tablets were evaluated using t...

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Reproductive Functions in Male Rats Treated With Methanolic Extract of Alstonia Boonei Stem Bark

The effects of methanolic extract of Alstonia boonei stem bark was studied on sperm characteristics, fertility, body and organ weights of adult albino rats. Oral administration of 50 and 200 mg/kg b.w/animal/day of the extract for 1, 2, 4, and 12 weeks caused duration and dose-dependent changes in the body weights, organ weights and sperm characteristics. However, there was a gradual increase i...

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Evaluation of Antimalarial Activity of Various Fractions of Morinda lucida Leaf Extract and Alstonia boonei Stem Bark

Investigation into antimalaria activity of various fractions of Morinda lucida leaf extract and Alstonia boonei stem bark was conducted using standard techniques. The present study confirms the antimalarial activity of Morinda lucida and Alstonia boonei. Morinda lucida exhibited MIC of 0.6mg/ml and Alstonia boonei MIC 0.2mg/ml. The anti plasmodia activity of both plants were found to reside maj...

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The Useful Medicinal Properties of the Root-Bark Extract of Alstonia boonei (Apocynaceae) May Be Connected to Antioxidant Activity

Folkloric use of root-bark extract of Alstonia boonei in the treatment and management of many disease conditions may be associated with free radical scavenging as part of its mechanisms of action. We therefore evaluated the ability of different solvent fractions of the methanol extract, crude precipitate from the extract, and isolated compound from the crude precipitate for scavenging 2,2-diphe...

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Antidepressant activity of methanol stem bark extract of Ficus platyphylla Del (Moraceae) in mice

Background & Aim: Depression is a heterogeneous mood disorder affecting both people in developing and developed countries. The drugs used in its management are associated with adverse effects and delayed response which compromise their therapeutic benefits. This makes it worthwhile to look for antidepressants plants with proven advantage and favourable benefit-...

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ژورنال

عنوان ژورنال: Agriculture and Biology Journal of North America

سال: 2013

ISSN: 2151-7517,2151-7525

DOI: 10.5251/abjna.2013.4.1.1.5